Andy Mesecar


    Andrew Mesecar
    Distinguished Professor of Biochemistry and Walther Professor in Cancer Structural Biology


    AFFILIATIONS: Biochemistry; Biological Sciences; PICR  
    OFFICE: HOCK 311
    LAB: HOCK xxx
    PHONE: 765-494-1924
    EMAIL: amesecar@purdue.edu


    Research

    The fundamental research interests of the Mesecar lab involve elucidating the molecular mechanisms and function of therapeutic enzymes and proteins. We wish to understand at the molecular level how enzymes and proteins recognize their substrates, catalyze their requisite chemical reactions, and trigger signal-transduction cascades. Our ultimate goal is to utilize this fundamental scientific knowledge to develop new therapeutics to treat cancer and infectious diseases.

    Links

    Biological Sciences Profile

    Mesecar Lab Website

     

Latest News

T32 Grant Funded Posted 01 June 2019
A Purdue Icon RESTS Posted 14 May 2019
CryoEM @ Purdue Posted 12 April 2019
cryoAPEX Posted 09 April 2019
ZIKA EXPOSED Posted 26 June 2018

About SCBB

Our group uses a wide variety of experimental approaches ranging from X-ray crystallography, NMR, Cryo-electron microscopy, electron tomography, and advanced spectroscopic techniques for examining and determining molecular structures, to computational techniques as they apply to nucleic acid and protein structures, bioinformatics, genomics and systems biology including molecular dynamics, machine learning, and network analysis.