Danzhou Yang


    Danzhou Yang
    Distinguished Professor of Medicinal Chemistry and Molecular Pharmacology


    AFFILIATIONS: Borch Department of Medicinal Chemistry and Molecular Pharmacology; Chemistry
    OFFICE: HANS 413B
    LAB: xxx
    PHONE: 765-494-8148
    EMAIL: yangdz@purdue.edu


    Research

    My research focuses on the structures and functions of biologically relevant DNA G-quadruplexes formed in the human oncogene promoters and human telomeres and their interactions with small molecules and proteins. We also work on structure-based rational design of anticancer drugs. We use NMR spectroscopy in combination with X-ray crystallography, cryo-EM, and other biophysical methods.

    Links

    MCMP Profile

    Yang Lab Website

     

Latest News

T32 Grant Funded Posted 01 June 2019
A Purdue Icon RESTS Posted 14 May 2019
CryoEM @ Purdue Posted 12 April 2019
cryoAPEX Posted 09 April 2019
ZIKA EXPOSED Posted 26 June 2018

About SCBB

Our group uses a wide variety of experimental approaches ranging from X-ray crystallography, NMR, Cryo-electron microscopy, electron tomography, and advanced spectroscopic techniques for examining and determining molecular structures, to computational techniques as they apply to nucleic acid and protein structures, bioinformatics, genomics and systems biology including molecular dynamics, machine learning, and network analysis.