Perry Paschou
Perry Paschou
Interim Head of Biological Sciences and Professor
AFFILIATIONS: Biological Sciences
OFFICE: LILY 1-225
LAB: xxx
PHONE: 765-494-4407
EMAIL: ppaschou@purdue.edu
Research
I work at the intersection of human population genetics, statistical analysis and genomic medicine, and my research interests lie in two main areas: first, I study the genetic basis of complex disorders in diverse human populations aiming to translate research findings into clinical applications and, second, using novel methods for large-scale data analysis, I investigate human genomic variation and population genetic relationships around the world.
Towards the first goal, a major focus of my research is the elucidation of the genetic background of neurodevelopmental phenotypes, such as Gilles de la Tourette Syndrome, autism, obsessive compulsive disorder and attention deficit hyperactivity disorder. I study genomewide datasets and I have a leading role in multiple large-scale collaborative efforts such as the EMTICS and TS-EUROTRAIN consortia. At the same time, working with neuropathologists and analyzing whole genome sequencing data, I also investigate the potential link between neurodegeneration and neurodevelopment.
On the other hand, working towards the decomposition of human genetic variation around the world, I investigate human evolution and the migration patterns of the human population across the globe and in particular population movements around the Mediterranean basin (GENOMAP.GR project). Interdisciplinarity is an important aspect of my work and I place particular emphasis on transferring algorithms and methodology from the fields of Computer Science and Applied Mathematics to population genetics and medical genetics. In an era of Big Data and the ability to mine the genome of hundreds of thousands of individuals, such approaches pave the way towards the direction of personalized medicine.
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